Achievements in development of prenatal diagnostics in republic of kazakhstan

Достижения в области развития пренатальной диагностики в Республике Казахстан
Zhanar Kurmangali 1, Kulyash Dzhamanaeva 2, Fred Ushakov 3, Talshyn Ukybasova 2, Almash Bekmuhametova 1, Aigul Sopbekova 1, Dias Saidangazin 1
More Detail
1 Republican diagnostic center of the corporate fund «UMC», Astana, Kazakhstan
2 National research center for maternal and child health of the corporate fund «UMC», Astana, Kazakhstan
3 University College London Hospital, London, UK
J CLIN MED KAZ, Volume 3, Issue 45 special issue, pp. 163-166.
Download Full Text (PDF)


This article presents the results of the three-year experience of the Fetal Medicine Center. For this period, non-invasive (20 911) and invasive methods of prenatal diagnosis (3 031) were conducted, aimed at early detection of congenital malformations and chromosomal abnormalities of the fetus, complications of pregnancy. In addition, it proposed a number of other important achievements of the Center Fetal Medicine in the field of prenatal diagnosis in the country.


Kurmangali Z, Dzhamanaeva K, Ushakov F, Ukybasova T, Bekmuhametova A, Sopbekova A, et al. Achievements in development of prenatal diagnostics in republic of kazakhstan. Journal of Clinical Medicine of Kazakhstan. 2017;3(45 special issue):163-6.


  • Health of the population of Republic of Kazakhstan and the activities of health organizations in 2015 [in Russian]. Statistical collection. Astana: Medinform LLP; 2016. 358 р.
  • Organization of prenatal screening [in Russian]. Order of the Minister of Health Republic Kazakhstan from September 09, 2010 №704. Retrieved from
  • International Society of Ultrasound in Obstetrics and Gynecology. Cardiac screening examination of the fetus: guidelines for performing the “basic” and “extended basic” cardiac scan. J Ultrasound Obstet Gynecol.2006;27:107–13.
  • Guidelines for the First Trimester Screening program. The Fetal Medicine Foundation. United Kingdom; 2008. 20 p.
  • ISUOG Practice Guidelines: Sonographic examination of the fetal central nervous system. J Ultrasound Obstet Gynecol.2007;29:109–16.
  • ISUOG Practice Guidelines (updated): Sonographic screening examination of the fetal heart. J Ultrasound Obstet Gynecol.2013;41:348–59.
  • ISUOG Practice Guidelines: Performance of first trimester fetal ultrasound scan. J Ultrasound Obstet Gynecol. 2013;41:102–13.
  • ISUOG Practice Guidelines: Use of Doppler ultrasonography in obstetrics. J Ultrasound Obstet Gynecol.2013;41:233–9.
  • American College of Obstetricians and Gynecologists. (2007a). Practice bulletin №77: screening for fetal chromosomal abnormalities. J Obstetrics and Gynecology.2007;109:217–7.
  • American College of Obstetricians and Gynecologists. (2007b). Practice bulletin №88: invasive prenatal testing for aneuploidy.J Obstetrics and Gynecology.2007;110:1459–67.
  • American College of Obstetricians and Gynecologists (2009). Practice bulletin №101: ultrasonography in pregnancy.J Obstetrics and Gynecology.2009;113:451–61.
  • ACOG Committee on Practice Bulletins. ACOG Practice Bulletin No. 77: screening for fetal chromosomal abnormalities.J Obstetrics and Gynecology.2007; 109:217–27.
  • NHS Fetal Anomaly Screening Programme – 18 +0 - 20 +6 week fetal anomaly scan. Guidance. NHS public health functions agreement 2016-17,from February 05, 2016; 33 р.
  • Ward P, Soothill P. Fetal anomaly ultrasound scanning: the development of a national programme for England. The Obstetrician &Gynaecologist. 2011;13:211-7.
  • On the approval of the Standards of Operational Procedures in the Department of Fetal Medicine and the Department of Management of Pregnant Women's Health Center [in Russian].Order of the director of the branch of the CF "UMC, from July 15, 2016 №84-ө.
  • Loureiro T., Ushakov F., Montenegro N., Gielchinsky Y., Nicolaides KH. Cerebral ventricular system in fetuses with open spina bifida at 11–13 weeks’ gestation. J Ultrasound Obstet Gynecol. 2012; 39(6):620-4.