Clinical and laboratory COVID-19 features in hospitalized patients with concomitant diabetes mellitus type 2: A retrospective study

Arailym Abilbayeva 1 * , Anel Tarabayeva 1, Gulzhana Idrisova 1, Aigul Abdrakhmanova 2, Ainur Sadykova 3, Ravilya Yegemberdiyeva 3, Amangul Duisenova 3
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1 Department of General Immunology, Asfendiyarov Kazakh National Medical University, Almaty Kazakhstan
2 City Clinical Infectious Diseases Hospital named after I.Zhekenova, Almaty, Kazakhstan
3 Department of Infectious and Tropical Diseases, Asfendiyarov Kazakh National Medical University, Almaty, Kazakhstan
* Corresponding Author
J CLIN MED KAZ, Volume 19, Issue 6, pp. 83-88. https://doi.org/10.23950/jcmk/12719
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ABSTRACT

Objective: To investigate the prevalence of diabetes mellitus in comorbidity structures and its effect on the clinical course in hospitalized COVID-19 patients in south region of Kazakhstan.
Material and methods: A retrospective analysis of data from 918 patients with COVID-19 treated at the City Clinical Infectious Diseases Hospital was carried out. Pearson's Chi-square test and Student's t-test were conducted.
Results: In Kazakhstan, diabetes mellitus occupies the second position in the structure of comorbidities in patients with COVID-19 with a share of 20%. Diabetes mellitus in patients most often occurs in combination with cardiovascular diseases and arterial hypertension (20.3% and 16.3%, respectively). Combination of diabetes mellitus, arterial hypertension and other diseases was detected in 72.4% of patients. Combination of diabetes mellitus, cardiovascular and other diseases was detected in 32.5%.
In diabetes mellitus patients, COVID-19 was more severe, the hospital stay was longer, and patients over 60 years of age suffered. These patients had a combination of diabetes mellitus with arterial hypertension, obesity, and cardiovascular diseases. Hyperglycemia, elevated blood pressure, rapid breathing, and low saturation were more common for these patients.
Conclusion: Diabetes mellitus ranks second in the structure of comorbidities in COVID-19 in the south region of Kazakhstan and is characterized by a combination with cardiovascular diseases, arterial hypertension and obesity. In patients with diabetes, COVID-19 is more severe, which affects the length of stay in the hospital, the mortality rate and the need for transfer to the Intensive Care Unit.

CITATION

Abilbayeva A, Tarabayeva A, Idrisova G, Abdrakhmanova A, Sadykova A, Yegemberdiyeva R, et al. Clinical and laboratory COVID-19 features in hospitalized patients with concomitant diabetes mellitus type 2: A retrospective study. J CLIN MED KAZ. 2022;19(6):83-8. https://doi.org/10.23950/jcmk/12719

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