Effect of pesticides on human health

Пестицидтердің адам денсаулығына әсері
Gauri Bapayeva 1, S Kulbayeva 2, A Zhumadilova 3
More Detail
1 Department of obstetrics and gynecology, National research center for maternal and child health of the corporate fund «UMC», Astana, Kazakhstan
2 South Kazakhstan State Pharmaceutical Academy, Shymkent, Kazakhstan
3 Akhmet Yassawi International Kazakh-Turkish University
J CLIN MED KAZ, Volume 3, Issue 45 special issue, pp. 128-132. https://doi.org/10.23950/1812-2892-JCMK-00494
OPEN ACCESS 3262 Views 2377 Downloads
Download Full Text (PDF)

ABSTRACT

Pesticides are unique chemicals, that deliberately spread in the environment and their toxicity has limited selectivity species.The Republic of Kazakhstan is a region where cotton is one of the most important sectors of agricultural production and textile industry, which in recent decades is experienced a new rise. Women are made up the largest part among the workers of this industry, which is concentrated in the south. For a long time in the cotton industry have been widely used organochlorine pesticides. The article presents a literature review of the effect of organochlorine pesticides on the human health, including the reproductive system.
Keywords: pesticides, reproductivehealth, human

CITATION

Bapayeva G, Kulbayeva S, Zhumadilova A. Effect of pesticides on human health. Journal of Clinical Medicine of Kazakhstan. 2017;3(45 special issue):128-32. https://doi.org/10.23950/1812-2892-JCMK-00494

REFERENCES

  • Mnif W., Hassine AI., Bouaziz A., Bartegi A., Thomas O., Roig B. Effect of endocrine disruptor pesticides. Int J Environ Res Public Health. 2011; 8:2265–2303.
  • Aripova T.U., Sirota A.R., Batyrbekov A.A. Immunitet i immunokorektsiya pri pestitsidnykh intoksikatsiyakh (Immunity and immunocorrection in pesticidal intoxications) [in Russian]. Tashkent. 2007. 272.
  • Babushkina N.P. Ekologiyagoroda I zdorov'edetei (Ecology of the city and children's health) [in Russian]. M.: MeditsinaZdorov'e; 2005; T.2. 259 p.
  • Belyaev E.N. Stoikieorganicheskiezagryazniteli, soderzhashchiesya v okruzhayushcheisrede, ikhvliyanienazdorov'enaseleniya (Persistent organic pollutants contained in the environment, their impact on human health) [in Russian]. EkologicheskiivestnikRossii. 2002;8:10-15.
  • Kul'baeva K.Zh. Ginekologiya detskogo i podrostkovogo vozrasta (Gynecology of children and adolescence) [in Russian]. Almaty: Evero. 2014. 276 p.
  • Salazar-Garcia F., Gallardo-Diaz E., Ceron-Mireles P. et al. Reproductive effects of occupational DDT exposure among male malaria control workers. Environ. HealthPersp. 2004; 112:542–547.
  • GichevYu.P. Zdorov'e cheloveka kak indicator ekologi i riska industrial'nykh regionov (Human health as an indicator of the ecology of the risk of industrial regions). Vestnik RAMN. 2005; 8: 52-54.
  • Sergeev O.V., Shelepchikov A.A., Denisova T.A. idr. Pilotnoe issledovanie soderzhaniya stoikikh zagryaznitelei v grudnom moloke zhenshchin Chapaevska (Pilot study of persistent contaminants in breast milk of Chapaevsk women) [in Russian]. Vestnik. Ros. VMA. 2008; 3:124-125.
  • Krauthaker B., Reiner E., and Votava-Raii A. et al. Organochlorine pesticides and PCB in human milk collected from mothers nursing hospitalized children. Chemosphere. 2004; 37: 27–32.
  • Stokgol'mskaya konventsiya o stoikikh organicheskikh zagryaznitelyakh (Stockholm сonvention on persistent organic pollutants) [in Russian]. 2001; http://dokipedia.ru
  • Hauser R., Chen Z., Pothier L. et al. The relationship between human semen parameters and environmental exposure to PCB and p, p1-DDE. Environ. Health Persp. 2003; 111: 1505–1511.
  • Milosevic-Djordjevic O., Grujicic D., Arsenijevic S., Brkic M., Ugrinovic S., Marinkovic D. Micronuclei in cord blood lymphocytes as a biomarker of transplacental exposure to environmental pollutants. Tohoku J Exp Med. 2007; 3(213); 231-239.
  • Gerunov T.V., Red'kinYu.V.,Gerunova L.K. Immunotoksichnost' pestitsidov: rol' v patologiizhivotnykh I cheloveka (Immunotoxicity of pesticides: a role in the pathology of animals and humans) [in Russian]. Uspekhsovremennoibiologii 2011; 1: 474-482.
  • Ivanenko N.V. Ekologicheskaya toksikologiya (Environmental toxicology) [in Russian]. http://abc.vvsu.ru/Books/ecolog_ tocsicolog/page0008.asp
  • Anne Williford, Kathryn J. DePaolis. Identifying Predictors of Instrumental and Reactive Aggression Among Low-Income Minority Adolescent Girls. Journal of the Society for Social Work and Research. 2012; 3 (3): 145-161.
  • Jarrell J., Villenenve D., Franklin C. et al. Contamination of human ovarian follicular fluid and serum by chlorinated organic compounds in three Canadian cities. J. Can. Med. Assoc. 2003; 148: 1321–1327.
  • Knowledge on Reproductive Health Issues among the Unmarried Adolescent Girls/ NasreenAktherandet. al. Journal of Family and Reproductive Health. 2012; 6(4); 69-176.
  • Fedorov L.A. Dioksiny kak ekologicheskaya opasnost': retrospektiva i perspektivy (Dioxins as an environmental hazard: a retrospective and perspective) [in Russian]. M.: Nauka; 2003. 266 p.
  • Ema M. and Miyawaki E. Adverse effects on development of the reproductive system in male offspring of rats given monobutyl phthalate, a metabolite of dibutyl phthalate, during late pregnancy. Reprod. Toxicol. 2001; 15: 189–194.
  • Gray L.E., Ostby J.S., Ferrell J.M. et al. A dose-response analysis of methoxychlor-induced alterations of reproductive development and function in the rat. Fund. Appl. Toxicol. 2006; 12: 92–108.
  • Baranov A.N., Lebedeva T.B. Mediko-ekologicheskie aspekty fizicheskogo i polovogo razvitiya (Medico-ecological aspects of physical and sexual development) [in Russian]. Zhurnal akusherstvaizhenskikhboleznei.2005; 1: 52-56.
  • Beskrovnaya N.I., Balasanyan I.G., Khrustaleva G.F., Svechnikova F.A. Tezisy № 31. Endokrinnaya sistema organizma i vrednye faktory vneshnei sredy (Endocrine system of the body and harmful environmental factors) [in Russian]. L.; 2003. 113 p.
  • Deng F., Tao F.B., Liu D.Y., Xu Y.Y., Hao J.H., Sun Y., et al. Effects of growth environments and two environmental endocrine disruptors on children with idiopathic precocious puberty. Eur J Endocrinol. 2012; 166: 803–809.
  • Sharpe R.H. and Skakkeback N.E. Are estrogens involved in falling sperm counts and disorders of the male reproductive tract? Lancet. 2005; 341: 1392–1395.
  • Nikitin A.I. Gormonopodobnyeksenobiotiki I reproduktivnaya Sistema (Hormon-like xenobiotics And Reproductive System) [in Russian]..Probl. reproduktsii. 2002; 2: 5-15.
  • Nikolaev A.A. Vozdeistvietekhnogennykhpollyutantovnaspermatoge-nez (The impact of technogenic pollutants on spermatogonia) [in Russian]. VestnikRos. VMA. 2008; 3:105.
  • Khokhlov P.P., Mikhnina E.A., Kalinina N.M. Znachenie immunofermentnogo opredeleniya autoantitel dlya diagnostiki zabolevaniir eproduktivnoi funktsii (The importance of immune-enzyme determination of autoantibodies for the diagnosis of reproductive diseases) [in Russian]. Rossiskiizhurnalimmunologii. 2007; 4: 144-145.
  • GafarovaD.Kh. Sostoyanie immunnoi sistemy devochek-podrostkov s zaderzhkoi fizicheskogo i polovogo razvitiya (The state of the immune system of adolescent girls with a delay and physical and sexual development)[in Russian]. Zhurnalteoreticheskoi iklinicheskoimeditsiny.2007; 2: 49-51.
  • Kozlova I.G. Immunologiya reproduktsii: teoreticheskie i klinicheskie aspekty (Immunology of reproduction: theoretical and clinical aspects)[in Russian]. Sankt-Peterburg: ELBI; 2007. 179 p.
  • Jacobson J.L. and Jacobson S.W. Intellectual impairment in children exposed to polychlorinated biphenyls in utero. N. Engl. J. Med. 2006; 335: 783–789.
  • Jarrell J., Villenenve D., Franklin C. et al. Contamination of human ovarian follicular fluid and serum by chlorinated organic compounds in three Canadian cities. J. Can. Med. Assoc. 2003; 148: 1321–1327.
  • Dolgikh O.V., Krivtsov A.V., Lykhina T.S. Osobennosti immunnogo i geneticheskogo statusa u zhenshchin v usloviyakh proizvodstva(Features of immune and genetic status in women under conditions of production) [in Russian]. Rossiiskiiimmunol ogicheskiizhurnal. 2012; 2(1): 50-52. 
  • Common Menstrual Problems among Slum Adolescent Girls of Western Maharashtra, India/ Ganganahalli P and et. al. Journal of Krishna Institute of Medical Sciences University. 2013; 02: 89-97.
  • Serov V.N., Kozhin A.A. Ekologo-generativnyi dissonans i patofiziologicheskie aspekty narushenii generativnoi funktsii tsentral'
  • nogo geneza. Akusherstvo i ginekologiya (Ecological-generative dissonance and pathophysiological aspects of violations of the generative function of central genesis. obstetrics and gynecology)[in Russian]. 2005; 8: 12–15.
  • Andreeva G.F., Ragimova O.A., Zhukova E.I. Poroki razvitiya novorozhdennykh v Saratovskoi populyatsii. Vliyanie antropogennykh faktorov na strukturnye preobrazovaniya kletok, tkanei i organov cheloveka i zhivotnykh (The influence of anthropogenic factors on structural transformations of human cells, tissues and organs)[in Russian]. Volgograd. 2005. 7–8 p.
  • Irgasheva S.U. Chastota i struktura narushenii polovogo razvitiya u devochek-podrostkovRespubliki Uzbekistan (The frequency and structure of violations and sexual development in adolescent girls in the Republic of Uzbekistan)[in Russian].Tsentral'noaziatskiinauchno-prakticheskiizhurnal. 2008; 3: 35-37.
  • Gusev A.A. Problemyekologo-ekonomicheskoibezopasnosti v Kurskoioblasti (Problems of ecological and economic security in the Kursk region) [in Russian]. Mediko-ekologicheskieInformatsionnyetekhnologii. 2004. 64-66 p.
  • Ostanin A.A. idr. Rol' tsitokinov v regulyatsi I sozrevaniyaootsitov. Tsitokinyivospalenie (The role of cytokines in regulating the maturation of oocytes) [in Russian]. 2005; 2: 86-87.
  • Bukovsky A. Oogenesis from human somatic stem cells and a role of immune adaptation in premature ovarian failure [in Russian]. Curr Stem Cell Res Ther; 2006; 3: 289-303.
  • Ho Y., Wigglesworth K., Eppig J.J., and Shultz R.M. Preimplantation development of mouse embryos in KSOM: augmentation by amino acids and analysis of gene expression. Mol. Reprod. Dev. 2005; 41: 232–238.
  • Cohn B.A., Wolff M.S., and Cirillo P.M. DDT and breast cancer in young women. Environ. Health Persp. 2007; 115: 1406–1414.
  • Upson K., De Roos A.J., Thompson M.L., Sathyanarayana S., Scholes D., Barr D.B., Holt V.L. Organochlorinepesticides and risk of endometriosis: findings from a population-based case-control study. Environ HealthPerspect. 2013;121: 1319-24.
  • Snijder C.A., teVelde E., Roeleveld N., Burdorf A. Occupational exposure to chemical substances and time to pregnancy: a systematic review. Hum Reprod Update. 2012;18: 284-300.
  • Wohlfahrt-Veje C., Main K.M., Schmidt I.M., Boas M., Jensen T.K., Grandjean P., Skakkebæk N.E., Andersen H.R. Lower birth weight and increased body fat at school age in children prenatally exposed to modern pesticides: a prospective study. Environ Health. 2011; 20: 10-79.
  • Jørgensen A., Nellemann Ch., Wohlfahrt-Veje Ch., Kold Jensen T., Katharina M. Main, HelleRaun Andersen. Interaction between paraoxonase 1 polymorphism and prenatal pesticide exposure on metabolic markers in children using a multiplex approach. Reproductive toxicology. 2015; 51: 22–30.
  • Koutroulakis D., Sifakis S., Tzatzarakis M.N., Alegakis A.K., Theodoropoulou E., Kavvalakis M.P., Kappou D., et al. phosphates in amniotic fluid as a biomarker of fetal exposure to organophosphates in Crete, Greece; association with fetal growth. Reproductive toxicology. 2014; 46: 98-105.
  • Gladen B.C., Klebanoff M.A., Hediger M.L., Katz S.H., Barr D.B., Davis M.D., et al. Prenatal DDT exposure in relation to anthropometric and pubertal measures in adolescent males. Environ Health Perspect. 2004; 112: 1761-1767.
  • Deng F., Tao F.B., Liu D.Y., Xu Y.Y., Hao J.H., Sun Y., et al. Effects of growth environments and two environmental endocrine disruptors on children with idiopathic precocious puberty. Eur J Endocrinol. 2012; 166: 803–809.
  • Ouyang F., Perry M.J., Venners S.A., Chen C., Wang B., Yang F., et al. Serum DDT, age at menarche and abnormal menstrual cycle length. Occup Environ Med. 2005; 62: 878–84.
  • Vasiliu O., Muttineni J., Karmaus W. In utero exposure to organochlorines and age at menarche. Hum Reprod. 2004; 19: 1506–12.
  • Vasiliu O., Muttineni J., Karmaus W. In utero exposure to organochlorines and age at menarche. Hum Reprod. 2004;19(7): 1506- 12.
  • John D. Meeker, ScD Exposure to Environmental Endocrine Disruptors and Child Development. Arch PediatrAdolesc Med. 2012; 166(10): 952-958.
  • Michael E. Baker and Gary Hardiman Transcriptional analysis of endocrine disruption using zebrafish and massively parallel sequencing. J MolEndocrinol. 2014. Vol. 52, №3. 241–256 p. doi:10.1530/JME-13-0219.
  • Denham M., Schell L.M., Deane G., Gallo M.V., Ravenscroft J., DeCaprioA.P. Relationship of lead, mercury, mirex, dichlorodi phenyldichloroethylene, hexachlorobenzene, and polychlorinated biphenyls to timing of menarche among Akwesasne Mohawk girls. Pediatrics. 2005;115: 127–134.
  • Perry M.J., Ouyang F., Korrick S.A., Venners S.A., Chen C., Xu X., Lasley B.L., Wang X. A prospective study of serum DDT and progesterone and estrogen levels across the menstrual cycle in nulliparous women of reproductive age. Am J Epidemiol. 2006; 164 (11): 1056-64.