Multislice computed tomography of potential liver donors

Мультиспиральная компьютерная томография у потенциальных доноров печени
Timur Sarsengaliyev 1, Boris Tsoy 1, Elmira Chuvakova 1
More Detail
1 Department of Radiology, JSC National Scientific Medical Research Center, Astana, Kazakhstan
J CLIN MED KAZ, Volume 2, Issue 44, pp. 42-46. https://doi.org/10.23950/1812-2892-JCMK-00374
OPEN ACCESS
Download Full Text (PDF)

ABSTRACT

Objective: Multislice computed tomography (MSCT) prior to liver transplantation is an important aspect of the diagnosis of changes in the liver as fat infltration, as well as visualization of the individual vascular anatomy and calculation of liver volume. The aim of our study was to analyze the results of the single center experience to conduct liver MSCT of donors who are preparing
for the transplant donation.
Methods: We studied the MSCT evaluation results of 39 (25 male and 14 female) potential liver donors’ during the 2015 - 2016 years. Liver MSCT with various standard renovations were used for more detailed visualization of blood vessels in each liver segment. Images were obtained on 64-slice MSCT (Aquilion; Toshiba Medical Systems, Tokyo, Japan). Interpretation of the results provided in accordance with embodiments of origin of the hepatic artery, portal vein anatomy and drainage of the hepatic veins.
Results: The main results of the anatomy of the hepatic artery, portal and hepatic veins are shown in Table 1, 2, 3. Based on the MSCT of 39 donor’s liver, 24 donors were identifed as appropriate for donation. 15 donors were contraindicated for donation due to: in 8 - were signs of fatty infltration, 2 donors - vascular anomaly of the portal vein, benign growths were detected in 5 donors.
Conclusion: MSCT is a primary diagnostic method for the preoperative planning of surgical resection of the liver, as well as preliminary identifcation of hepatic pathology. According to the results and experience of our center, in 61.5% cases, liver donors were selected for donation and remaining 38.5% of the donors were excluded from organ donation, in connection with the identifed contraindications.

CITATION

Sarsengaliyev T, Tsoy B, Chuvakova E. Multislice computed tomography of potential liver donors. Journal of Clinical Medicine of Kazakhstan. 2017;2(44):42-6. https://doi.org/10.23950/1812-2892-JCMK-00374

REFERENCES

  • Singer PA, Siegler M, Whitington PF, et al. Ethics of liver transplantation with living donors. N Engl J Med. 1989;321(9):620- 622.
  • Strong RW, Lynch SV, Ong TH, Matsunami H, Koido Y, Balderson GA. Successful liver transplantation from a living donor to her son. N Engl J Med. 1990;322(21):1505-1507.
  • Broelsch CE, Burdelski M, Rogiers X, et al. Living donor for liver transplantation. Hepatology. 1994;20(1 Pt 2):49S-55S.
  • Hashikura Y, Makuuchi M, Kawasaki S, et al. Successful living-related partial liver transplantation to an adult patient. Lancet. 1994;343(8907):1233-1234.
  • Kawasaki S, Makuuchi M, Matsunami H, et al. Living related liver transplantation in adults. Ann Surg. 1998;227(2):269-274.
  • Got’e S, Konstantinov B, Tsirul’nikova O. Transplantatsiya pecheni (Liver transplantation). M.: Meditsinskoe informatsionnoe agentstvo. 2008
  • Abramova N, Muslimov R, Uvarov K. Mul’tispiral’naya komp’yuternaya tomografya v bsledovanii donorov pri transplantatsii fragmenta pecheni ot zhivogo rodstvennogo donora (Multispiral computed tomography in a donor survey for the transplantation of a liver fragment from a living related donor). Vestnik transplantologii i iskusstvennykh organov. 2009;11(3):37- 41.
  • Emond JC, Renz JF, Ferrell LD, et al. Functional analysis of grafts from living donors. Implications for the treatment of older recipients. Ann Surg. 1996;224(4):544-552; discussion 552-544.
  • Zajko AB, Bron KM, Starzl TE, et al. Angiography of liver transplantation patients. Radiology. 1985;157(2):305-311.
  • Lee SS, Kim TK, Byun JH, et al. Hepatic arteries in potential donors for living related liver transplantation: evaluation with multidetector row CT angiography. Radiology. 2003;227(2):391-399.
  • Winter TC, 3rd, Nghiem HV, Freeny PC, Hommeyer SC, Mack LA. Hepatic arterial anatomy: demonstration of normal supply and vascular variants with three-dimensional CT angiography. Radiographics. 1995;15(4):771-780.
  • Winter TC, 3rd, Freeny PC, Nghiem HV, et al. Hepatic arterial anatomy in transplantation candidates: evaluation with threedimensional CT arteriography. Radiology. 1995;195(2):363-370.
  • Lemke AJ, Brinkmann MJ, Schott T, et al. Living donor right liver lobes: preoperative CT volumetric measurement for calculation of intraoperative weight and volume. Radiology. 2006;240(3):736-742.
  • Nakayama Y, Li Q, Katsuragawa S, et al. Automated hepatic volumetry for living related liver transplantation at multisection CT. Radiology. 2006;240(3):743-748.
  • Mizandari M, Mtvaradze A, Urushadze O, Maisaya K, Todua F. Kompleksnaya luchevaya diagnostika diffuz noi patologii pecheni (zhirovoi gepatoz, khronicheskii gepa tit, tsirroz) (Complex radiation diagnosis of diffuse liver pathology (fatty hepatosis, chronic hepatitis, cirrhosis)). Med. vizualizatsiya. 2002;1(6):66.
  • Raptopoulos V, Karellas A, Bernstein J, Reale FR, Constantinou C, Zawacki JK. Value of dual-energy CT in differentiating focal fatty infiltration of the liver from low-density masses. AJR Am J Roentgenol. 1991;157(4):721-725.
  • Bydder GM, Chapman RW, Harry D, Bassan L, Sherlock S, Kreel L. Computed tomography attenuation values in fatty liver. J Comput Tomogr. 1981;5(1):33-35.
  • Levi C, Gray JE, McCullough E, Hattery R. The unreliability of CT numbers as absolute values. American Journal of Roentgenology. 1982;139(3):443-447.
  • Soyer P, Bluemke DA, Choti MA, Fishman EK. Variations in the intrahepatic portions of the hepatic and portal veins: findings on helical CT scans during arterial portography. AJR Am J Roentgenol. 1995;164(1):103-108.
  • Michels NA. Newer anatomy of the liver and its variant blood supply and collateral circulation. Am J Surg. 1966;112(3):337-347.
  • Erbay N, Raptopoulos V, Pomfret EA, Kamel IR, Kruskal JB. Living donor liver transplantation in adults: vascular variants important in surgical planning for donors and recipients. AJR Am J Roentgenol. 2003;181(1):109-114.