Postoperative complications after liver resection in patients with focal lesions

Nurbek Ilyassov 1 2 *
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1 Department of General and Thoracic Surgery, National Scientific Medical Center, Nur-Sultan city, Republic of Kazakhstan
2 №2 Department of Surgical Diseases, Medical University Astana, Nur-Sultan city, Republic of Kazakhstan
* Corresponding Author
J CLIN MED KAZ, Volume 1, Issue 55, pp. 32-35.
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Aims: To study the main complications in the immediate postoperative period after resection of the liver of various sizes in patients with focal diseases. To conduct a comparative analysis of the frequency of complications depending on the volume of surgical intervention and the assessment of prognostic factors for the timely detection of post-resection complications.
Material and methods: A retrospective analysis was performed in 97 patients with focal liver diseases who were undergoing surgical treatment from 2010 to 2016. Of 97 patients undergoing liver resection, 26 noted various complications in the immediate postoperative period.
Results: The most common complication is suppuration of the surgical wound (37.1%), pleural effusion (22.6%), liver failure (19.5%), persistent ascites (7.2%), less common complications included biliary fistulas (2%), thrombophlebitis (2%) and intra-abdominal bleeding (1%). An important point affecting the results of surgical treatment was the volume of the resected liver, respectively, and the complication rate reached in 33.3% - 50% of cases.
Conclusion: A connection was found between the use of extensive liver resection, a change in the immunological status and the occurrence of various complications, despite the standard management of patients.


Ilyassov N. Postoperative complications after liver resection in patients with focal lesions. Journal of Clinical Medicine of Kazakhstan. 2020;1(55):32-5.


  • Vishnevskii VA, Nazarenko HA, Chzhao A.B et al. Extensive resections with metastatic liver damage [in Russian]. Annaly khirurgicheskoi gepatologii. 1999; 4(2):185-186.
  • Cohnert TU, Rau HG, Buttler E, et al. Preoperative assessment of hepatic resection for alignant disease. J. Surg. 1997; 21(4):396-401.
  • Fabbrucci P, Androsoni G, Falchi A. Liver resection with the water dissector: preliminary experience of 8 cases. Ann Ital Chir. 1999; 70(1):99-103.
  • Shimada M, Matsumata T, Akazawa K. et al. Estimation risk of major complications after hepatic resection. Amer. J. Surg. 1994;167(4):399-403.
  • Kim YJ, Nakashima K, Tada I, et al. Prolonged normothermic ischaemia of human cirrhotic liver during hepatectomy: a preliminary report. Br. J. Surg. 1993; 80:1566-1570.
  • Pinkerton JA, Sawyers JL, Foster JH. A study of the postoperative course after hepatic lobectomy. Ann. Surg. 1971; 173(5):800-811.
  • Segawa T, Tsuchiya R, Furui J. et al. Operative results in 143 patients with hepatocellular carcinoma. World J. Surg. 1993; 17(5):663-667.
  • Capussotti L, Borgonovo G, Bouzari H, et al. Result of major hepatectomy for large primary liver cancer in patients with cirrhosis. Brit. J. Surg. 1994; 81(3):427-431.
  • Hu RH, Lee PH, Yu SC. et al. Surgical resection for hepatocellular carcinoma: prognosis and analisis of risk factors. Surgery. 1996; 120(1):23-29.
  • Matsumata T, Kanematsu T, Okudarira Y. et al. Postoperative mechanical ventilation preventing the occurrence of pleural effusion after hepatectomy. Surgery. 1987; 102(3)493-497.
  • Uetsuji S, Komada Y, Kwon AH. et al. Prevention of pleural effusion after hepatectomy using fibrin sealant. Int. Surg. 1994; 79(2):135-137.
  • Nagasue N, Yukaya H, Ogawa Y, Sasaki Y. et al. Clinical experience with 118 hepatic resections for hepatocellular carcinoma. Surgery. 1986; 99(6):694-701.
  • Pirte J, Houssin D, Kracht M. Resection of hepatocellular carcinomas. Analysis of prognostic factors of a multicenter series of 153 patients. Gastroenterol. Clin. Biol. 1993;17(3):200-206.
  • Yamanaka N, Okamoto E. et al. A prediction scoring system to select the surgical treatment of liver cancer. Further refinement based 10 years of use. Ann. Surg. 1994; 219(4)342-346.
  • Rabes HM, Tuczek HV, Wirshing R. Liver regeneration after experimental injury. New York: Grune&Stratton. 1979; 35-52.
  • Roger V, Balladur P, Honiger J, Delelo R, Baudri-rnont M. et al. A good model of acute hepatic failure: 95% hepatectomy. Treatment by transplantation of hepatocytes. Chirurgie. 1996; 121(6)470-473.
  • Gertsch P, Stipa F, Ho J, Yuen ST, Luk I, et al. Changes in hepatic portal resistance and liver morphology during regeneration: in vitro study in rats. Eur. J. Surg. 1907; 163(4):297-304.
  • Panis Y, McMulIan DM, Emond JC. Progressive necrosis after hepatectomy and the pathophysiology of liver failure after massive resection. Surgery. 1997; 121(2):142-149.
  • Van-Leeuwen PA, Hong RW, Rounds JD. et al. Hepatic failure and coma after liver resection is reversed by manipulation of gut contents: the role of endotoxin. Surgery. 1991; 110(2):169-175.
  • Klein AS, Smith GW. Diagnostic operations of the liver and techniques of hepatic resection. In: Shacklefords Surgery of the Alimentary Tract. Saunders. 1996; 578-599.
  • Williams R. Treatment of acute liver failure. In: Arroyo V, Bosch J, Rodes J. Treatments in Hepatolo-gy. Barcelone: Masson. 1995; 365-374.
  • Patyutko YuI, Panakhov DM. Prognosis factors for primary malignant tumors of the liver [in Russian]. Annaly khirurgicheskoi gepatologii. 1997; 2:25-31.
  • Wu CC, Ho WL. Yeh DS. et al. Hepatic resection of hepatocellular carcinoma in cirrhotic livers: is it unjustified in impaired liver function? Surgery. 1996; 120(1):34-39.