Prognostic value of blood gas lactate levels among COVID-19 patients

Nihat Müjdat Hökenek 1, Rohat Ak 1 *
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1 Department of Emergency Medicine, Kartal Dr. Lütfi Kırdar City Hospital, Istanbul, Turkey
* Corresponding Author
J CLIN MED KAZ, Volume 18, Issue 4, pp. 87-90. https://doi.org/10.23950/jcmk/11130
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ABSTRACT

Objective: Our aim in this study to determine the relationship between the blood gas lactate values of the patients who have 2019 coronavirus disease (COVID-19) at the time of admission to the emergency department (ED) and the mortality status of these patients and the intensive care unit (ICU) requirement.
Methods: This retrospective observational study was conducted with patients who were diagnosed with COVID-19 in the emergency department of a tertiary hospital. The study was continued with the remaining 292 patients after using the inclusion and exclusion criteria. Patients included in the study were divided into 2 groups according to their lactate levels (Lactate ≤ 2 mmol/L and Lactate > 2 mmol/L). Then we compared the groups according to their ICU requirement and mortality status.
Results: There were 292 patients included in this study. The mean age of the patients was 68.3 ± 15.9, of which 158 were men and 134 were women.  Hyperlactatemia (lactate >2) was found in 136 (46.6%) of the 292 patients included in the study, while 156 (53.4%) had normal lactate levels (lactate ≤2). The most common comorbidities in the patients were hypertension (HT), diabetes mellitus (DM), and cardiovascular diseases. ICU requirements and mortality status of the patients in the study, when compared with lactate levels, the mortality and ICU rates of the hyperlactatemia group were statistically higher.
Conclusion: Our study found that hyperlactatemic COVID-19 patients had higher ICU requirement and mortality rates compared to non-hyperlactatemic patients. Prospective studies with larger sample sizes are necessary to adequately assess the relationship between lactate and mortality in COVID-19 patients.

CITATION

Hökenek NM, Ak R. Prognostic value of blood gas lactate levels among COVID-19 patients. J CLIN MED KAZ. 2021;18(4):87-90. https://doi.org/10.23950/jcmk/11130

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