Respiratory muscle strength in Hashimoto's disease

Seda Beyhan Sagmen 1 * , Naile Gokkaya 2
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1 Department of Pulmonary Medicine, Kartal Dr. Lutfi Kirdar Training and Research Hospital, Health Science University, Istanbul, Turkey
2 Department of Endocrinology and Metabolic Diseases, Kartal Dr. Lutfi Kirdar Training and Research Hospital, Health Science University, Istanbul, Turkey
* Corresponding Author
J CLIN MED KAZ, Volume 6, Issue 60, pp. 63-67. https://doi.org/10.23950/jcmk/9264
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ABSTRACT

Objective: The present study aimed to investigate the respiratory function and respiratory muscle strength in Hashimoto's disease.
Material and methods: Thirty-two patients newly diagnosed with Hashimoto’s disease between January 2017 and July 2017 were included in this study. Pulmonary function tests were also performed. FEV1 / FVC, FEV1%, FEV1 (1/sec), FVC (%), FVC (1), DLCO, DLCO/VA, maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP) values were examined.
Results: The mean age of the hypothyroid group was 43 (36-45), and the euthyroid group was 40 (35-46) years. The DLCO/VA level [86.00 (79.00-99.00)] in the hypothyroid group was significantly lower than the euthyroid group [99.00 (95.00-115.00)] (p: 0.007). MIP level in the hypothyroid group [75.00 (69.00-79.00)] was significantly lower than the euthyroid group [99.00 (83.00-112.00)] (p: 0.008). A negative correlation was found between TSH and DLCO, DLCO/VA and MIP (r: -0.376, p: 0.034; r: -0.499, p: 0.004 and r: -0.378, p: 0.033). A positive correlation was found between T4 and DLCO and DLCO/VA (r: 0.390, p: 0.027 and r: 0.351, p: 0.049, respectively).
Conclusion: In light of the data obtained in this study, the findings suggest that hypothyroidism affects respiratory muscle strength, and this weakness is associated with thyroid hormone levels

CITATION

Sagmen SB, Gokkaya N. Respiratory muscle strength in Hashimoto's disease. J Clin Med Kaz. 2020;6(60):63-7. https://doi.org/10.23950/jcmk/9264

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