Some aspects of lifestyle as predictors of malignant neoplasms of upper gastrointestinal tract
Некоторые особенности образа жизни как предикторы злокачественных новообразований верхних отделов желудочно-кишечного тракта
Galiya Orazova 1 2, Leonid Karp 1, Alikhan Dossakhanov 2, Lyaziza Sauyekenova 3, Gulnara Zhaxylykova 3, Larisa Bukhanovskaya 4, Alma Zhylkaydarova 5, E. Zhapparov 6
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1 Astana Medical University, Astana, Kazakhstan
2 National Scientific Medical Research Center, Astana, Kazakhstan
3 Ministry of Healthcare and Social Development of the Republic of Kazakhstan, Astana, Kazakhstan
4 Municipal Polyclinic 6 of Astana city, Astana, Kazakhstan
5 Кazakh Scientific Research Institute of Oncology and Radiology, Almaty, Kazakhstan
6 Oncology Center of Astana city, Astana, Kazakhstan
J CLIN MED KAZ, Volume 1, Issue 35, pp. 45-50.
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ABSTRACT
Purpose of the study. Identification of lifestyle aspects of population as predictors of malignant neoplasms of upper gastro-intestinal tract.
Methods. This study is a cross-sectional one. There were selected respondents between 40-59 years old (here in after the total population) to creating a profile of population. During the study of risk factors for cancer of the upper gastrointestinal tract there were used specially developed questionnaire for general population and for cancer patients who were examined and treated in cancer clinics in the several regions of the country. In total there were surveyed 1.112 respondents of population and 403 patients with cancer of the upper gastrointestinal tract. The frequency of risk factors was obtained with the confidence interval (±). Comparison of the frequency factor indicators was carried out by Student’s formula.
Results. Almost half of the respondents of the total population and 72.7% of patients noted the presence of any disease of gastrointestinal tract in close relatives. Almost 2/3 of the patients indicated that in the past medical history often used the fat, salt, canned food and had social habits. In both sets of age groups men smoke more than women. It was found that the proportion of ever-smokers in the cities significantly higher than the percentage of the rural population. Approximately one third of respondents noted the presence of subjective emotional stress.
Conclusions. During the study of lifestyle of the general population and patients with malignant neoplasms revealed a number of differences, which can be considered as predictors of cancer process.
CITATION
Orazova G, Karp L, Dossakhanov A, Sauyekenova L, Zhaxylykova G, Bukhanovskaya L, et al. Some aspects of lifestyle as predictors of malignant neoplasms of upper gastrointestinal tract. Journal of Clinical Medicine of Kazakhstan. 2015;1(35):45-50.
REFERENCES
- Lagergren J, Ye W, Lindgren A, Nyrén O. Heredity and risk of cancer of the esophagus and gastric cardia, Cancer Epidemiol Biomarkers Prev, 2000; No.9, pp.757-760.
- Dhillon PK, Farrow DC, Vaughan TL, et al. Family history of cancer and risk of esophageal and gastric cancers in the United States, Int J Cancer, 2001, No. 93, pp.148-152.
- Ji J, Hemminki K. Familial risk for esophageal cancer: an updated epidemiologic study from Sweden, ClinGastroenterolHepatol, 2006, No.4, pp.840-845.
- Marjani HA, Biramijamal F, Hossein-Nezhad A, et al. Prevalence of esophageal cancer risk factors among Turkmen and nonTurkmen ethnic groups in a high incidence area in Iran, Arch Iran Med, 2010, No.13, pp.111-115.
- Engel LS, Chow WH, Vaughan TL, et al. Population attributable risks of esophageal and gastric cancers, J Natl Cancer Inst, 2003, No.95, pp.1404-1413.
- Brown LM, Hoover R, Gridley G, et al. Drinking practices and risk of squamous-cell esophageal cancer among Black and White men in the United States, Cancer Causes Control, 1997, No.8, pp.605-609.
- Gammon MD, Schoenberg JB, Ahsan H, et al. Tobacco, alcohol, and socioeconomic status and adenocarcinomas of the esophagus and gastric cardia, J Natl Cancer Inst, 1997, No.89, pp.1277-1287.
- Pandeya N, Williams G, Green AC, et al. Alcohol consumption and the risks of adenocarcinoma and squamous cell carcinoma of the esophagus, Gastroenterology, 2009, No.136, pp.1215-1224.
- Park B, Shin A, Park SK, et al. Ecological study for refrigerator use, salt, vegetable, and fruit intakes, and gastric cancer, Cancer Causes Control, 2011, No.22, pp.1497-1502.
- Yang P, Zhou Y, Chen B, et al. Overweight, obesity and gastric cancer risk: results from a meta-analysis of cohort studies, Eur J Cancer, 2009, No.45, pp.2867-2873.
- World Cancer Research Fund/American Institute for Cancer Research (2007). Food, Nutrition, Physical Activity, and the Prevention of Cancer: A Global Perspective. World Cancer Research Fund/American Institute for Cancer Research: Washington DC.
- Heikkilä, K., Nyberg, S. T., Theorell, T. et al. Work stress and risk of cancer: meta-analysis of 5700 incident cancer events in 116,000 European men and women, BMJ, 2013, T.346, f165.
- Hamashima C, Saito H, Nakayama T, et al. The standardized development method of the Japanese guidelines for cancer screening, Jpn J Clin Oncol, 2008, No.38, pp.288-295.
- Mizoue T, Yoshimura T, Tokui N, et al. Prospective study of screening for stomach cancer in Japan, Int J Cancer, 2003, No.106, pp.103-107.
- Larsson SC, Orsini N, Wolk A. Processed meat consumption and stomach cancer risk: a meta-analysis, J Natl Cancer Inst, 2006, No.98, pp.1078-1087.
- Zhao L, Blot WJ, Liu WD, et al. Familial predisposition to precancerous gastric lesions in a high-risk area of China, Cancer Epidemiol Biomarkers Prev, 1994, No.3, pp.461-464.
- Tsugane S, Sasazuki S. Diet and the risk of gastric cancer: review of epidemiological evidence, Gastric Cancer, 2007, No.10, pp.75-83.
- Tramacere I, La Vecchia C, Negri E. Tobacco smoking and esophageal and gastric cardiaadenocarcinoma: a meta-analysis, Epidemiology, 2011, No. 22, pp.344-349.
- M A M, Pera G, Agudo A, et al. Cereal fiber intake may reduce risk of gastric adenocarcinomas: the EPIC-EURGAST study, Int J Cancer, 2007, No.121, pp.1618-1623.
- Islami F, Boffetta P, Ren JS, et al. High-temperature beverages and foods and esophageal cancer risk—a systematic review, Int J Cancer, 2009, No. 125, pp.491-524.
- Islami F, Pourshams A, Nasrollahzadeh D, et al. Tea drinking habits and oesophageal cancer in a high risk area in northern Iran: population based case-control study, BMJ, 2009, T.338, b929.