The effect of inflammatory markers on the CORADS degree and the effects of treatments on RT-PCR test results in COVID-19

Hatice Hamarat 1 * , Özge Alkan Tali 1, Berrin Yalınbaş Kaya 2, Aral Karabağ 3, Rabiye Altınbaş 4
More Detail
1 Internal Medicine Department, Eskişehir City Hospital, Eskişehir, Turkey
2 Gastroenterology Department, Eskişehir City Hospital, Eskişehir, Turkey
3 Radiology Department, Eskişehir City Hospital, Eskişehir, Turkey
4 Microbiology Department, Eskişehir City Hospital, Eskişehir,
* Corresponding Author
J CLIN MED KAZ, Volume 19, Issue 5, pp. 42-47. https://doi.org/10.23950/jcmk/12524
OPEN ACCESS
Download Full Text (PDF)

ABSTRACT

Objective: There is still no diagnosis method with high sensitivity and specificity for COVID-19. Patient complaints, real-time reverse transcription-polymerase chain reaction (RT-PCR), inflammatory markers, clinical prognosis, and the degree of involvement in the chest CT, if necessary are evaluated in an effort to make a diagnosis. Delays in diagnosis have led to a rapid spread of the disease. This study aims to evaluate the effectiveness of the inflammatory markers and to determine the follow-up process of the patients by assessing the impact of the treatments administered on RT-PCR test results.
Material and methods: Files of 150 patients monitored in the wards with suspected COVID-19 are analyzed retrospectively. Patients were selected among those who underwent laboratory tests, RT-PCR testing and Thoracic CT within the first 24 hours of admission. Patients were divided into 5 groups based on the severity of involvement in Thoracic CT. Inflammatory markers were compared among the groups. Impact of the administered treatments on follow-up RT-PCR test results was evaluated.
Results: Studied inflammatory markers were in normal ranges and similar across all CORADS groups. Only the C-Reactive Protein (CRP) and Ferritin levels were showing an increase in accordance with CORADS severity. Mean time to testing negative on RT-PCR was 10 days across all treatment groups. Times to testing negative among patients receiving other treatments were similar.
Conclusion: Among the inflammatory markers, CRP and Ferritin values are correlated with CORADS severity. Administered COVID-19 treatments have similar impact on RT-PCR test results.

CITATION

Hamarat H, Tali ÖA, Kaya BY, Karabağ A, Altınbaş R. The effect of inflammatory markers on the CORADS degree and the effects of treatments on RT-PCR test results in COVID-19. J CLIN MED KAZ. 2022;19(5):42-7. https://doi.org/10.23950/jcmk/12524

REFERENCES