The Effect of Postmenopausal Therapeutic Interventions on Sexual Function: a Meta-analysis Study
Sibel Yücetürk 1 * ,
Nurten Özçalkap 2,
Ayşe Çuvadar 3,
Yeter Çuvadar Baş 4 More Detail
1 Department of Midwifery, Faculty of Health Sciences, Sinop University, Sinop, Turkey
2 Department of Midwifery, Faculty of Health Sciences, Ağri Ibrahim Cecen University, Ağri, Turkey
3 Department of Midwifery, Faculty of Health Sciences, Karabuk University, Karabuk, Turkey
4 Vacational School, Gedik University, Istanbul, Turkey
* Corresponding Author
J CLIN MED KAZ, Volume 23, Issue 2, pp. 72-78.
https://doi.org/10.23950/jcmk/18011
OPEN ACCESS
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Author Contributions: Conceptualization, S.Y., N.Ö., A.Ç. and Y.Ç.B.; methodology, S.Y., N.Ö., A.Ç. and Y.Ç.B.; validation, S.Y., N.Ö., A.Ç. and Y.Ç.B.; formal analysis, S.Y., N.Ö., A.Ç. and Y.Ç.B.; investigation, S.Y., N.Ö., A.Ç. and Y.Ç.B.; resources, S.Y., N.Ö., A.Ç. and Y.Ç.B.; data curation, S.Y., N.Ö., A.Ç. and Y.Ç.B.; writing – original draft preparation, S.Y., N.Ö., A.Ç. and Y.Ç.B.; writing – review and editing, S.Y., N.Ö., A.Ç. and Y.Ç.B.; visualization, S.Y., N.Ö., A.Ç. and Y.Ç.B.; supervision, S.Y., N.Ö., A.Ç. and Y.Ç.B.; project administration, S.Y., N.Ö., A.Ç. and Y.Ç.B.; funding acquisition, S.Y., N.Ö., A.Ç. and Y.Ç.B. All authors have read and agreed to the published version of the manuscript.
Data availability statement: All data analyzed in this meta-analysis were derived from previously published studies accessible through academic databases. No new datasets were generated.
Artificial Intelligence (AI) Disclosure Statement: The authors declare no AI Tools used for preparation of this work.
ABSTRACT
Aim: The purpose of this study is to identify how therapeutic interventions after menopause affect sexual function.
Methods: For this study, research was conducted by screening studies in PubMed, Web of Science, EBSCOhost, Google Scholar, and YOK Thesis Center databases from May to July 2024. After reviewing the studies, five researchers were included in the study. The quality assessment of the studies was conducted using a quality assessment tool prepared by The Joanna Briggs Institute, according to Randomized Controlled Trials and Quasi-Experimental design studies. CMA Version 2 was used for data synthesis. The data were synthesized using meta-analysis and narrative synthesis methods.
Results: According to the results of the meta-analysis, therapeutic interventions applied during the postmenopausal period were found to not be effective on sexual function (SMD: 1.056, 95% CI: -0.171 to 2.282; Z= 1.686, p = 0.092, I2= 97.827%). However, in subgroup analyses, it was determined that Pelvic Floor Exercises were effective in women with sexual dysfunction.
Conclusion: While pelvic floor muscle training (PFMT) appears to be a promising intervention for improving postmenopausal sexual dysfunction, this finding is based on limited evidence and should be interpreted with caution. Given the variability in intervention types and study quality, further high-quality randomized controlled trials are needed to evaluate the comparative effectiveness of PFMT and other therapeutic approaches, as well as their potential combinations, in order to establish more definitive conclusions.
CITATION
Yücetürk S, Özçalkap N, Çuvadar A, Çuvadar Baş Y. The Effect of Postmenopausal Therapeutic Interventions on Sexual Function: a Meta-analysis Study. J CLIN MED KAZ. 2026;23(2):72-8.
https://doi.org/10.23950/jcmk/18011
REFERENCES
- Asmin N, Sultana S, Habib SH, Khatun KH. Intervention approach to the menopausal women in rural Bangladesh. Bangladesh Med J. 2009;38:9-14. https://doi.org/10.3329/bmj.v38i1.3580. https://banglajol.info/index.php/BMJ/article/view/3580.
- Keriman N. The effectiveness of fennel on the sexual health of postmenopausal women: a systematic review study. Iran J Obstet Gynecol Infertility. 2022;25(3):9. https://ijogi.mums.ac.ir/article_20430_en.html.
- *Nazarpour S, Simbar M, Majd HA, Tehrani FR. Beneficial effects of pelvic floor muscle exercises on sexual function among postmenopausal women: A randomised clinical trial. Sex Health. 2018;15:396–402. https://doi.org/10.1071/SH17203. https://connectsci.au/sh/article-lookup/doi/10.1071/sh17203.
- World Health Organization. Defining sexual health. Report of a technical consultation on sexual health, 28-31 January 2002, Geneva. Sexual health document series. Geneva, 2006:35. https://www.scirp.org/reference/ReferencesPapers?ReferenceID=1998000. Accessed September 10, 2025.
- Tehrani FR, Farahmand M, Simbar M, Afzali HM. Factors associated with sexual dysfunction; a population-based study in Iranian reproductive age women. Arch Iran Med. 2014;17:679–84. https://pubmed.ncbi.nlm.nih.gov/25305767/.
- Stephenson KR, Kerth J. Effects of mindfulness-based therapies for female sexual dysfunction: A meta-analytic review. The Journal Of Sex Research. 2017;54(7):832–849. https://doi.org/10.1080/00224499.2017.1331199.
- Castelo-Branco C, Blumel JE, Araya H, Riquelme R, Castro G, Haya J, Gramegna G. Prevalence of sexual dysfunction in a cohort of middle-aged women: influences of menopause and hormone replacement therapy. J Obstet Gynaecology: J Inst Obstet Gynecol. 2003;23(4):426–30. https://www.tandfonline.com/doi/abs/10.1080/0144361031000120978
- Laan E, Both S. Sexual desire and arousal disorders in women. Adv Psychosom Med. 2011;31:16–34. https://doi.org/10.1159/000328806. https://pubmed.ncbi.nlm.nih.gov/22005202/
- Zarski AC, Velten J, Knauer J, Berking M, Ebert DD. Internet- and mobile-based psychological interventions for sexual dysfunctions: a systematic review and meta-analysis. NPJ Digital Medicine. 2022;5:139. https://doi.org/10.1038/s41746-022-00670-1.
- Thornton K, Chervenak J, Neal-Perry G. Menopause and sexuality. Endocrinol Metab Clin North Am 2015; 44: 649–661. https://www.endo.theclinics.com/article/S0889-8529(15)00050-X/abstract
- Mroczek B. Kurpas D. Gronowska M. Kotwas A. Psychosexual needs and sexual behaviors of nursing care home residents. Archives of Gerontology and Geriatrics. 2013;(57):32-38. https://www.sciencedirect.com/science/article/pii/S0167494313000265
- Basson R. Sexual dysfunctions in women: Are androgens at fault? Endocrinol Metab Clin N Am. 2021;50:125–138. https://doi.org/10.1016/j.ecl.2020.12.001. https://www.endo.theclinics.com/article/S0889-8529(20)30089-X/abstract
- Turhan İ, Akcan K. Current diagnosis and treatments of female sexual dysfunction. Gevher Nesıbe Journal Of Medical & Health Sciences. 2022;7(17):57–63. https://doi.org/https://doi.org/10.46648/gnj.384.
- Moher D, Liberati A, Tetzlaff J, Altman DG. PRISMA Group, 2009. Reprint—preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Physical Therapy. 2009;89:873-880. https://doi.org/10.1371/journal.pmed.1000097. https://www.bmj.com/content/339/bmj.b2535.short
- The Joanna Briggs Institute Critical Appraisal Tools for use in IBI Systematic Reviews. http://joannabriggs.org/research/critical-appraisal-tools.html. Accessed September 10, 2025.
- Tufanaru C, Munn Z, Aromataris E, Campbell J, Hopp L. Chapter 3: Systematic reviews of effectiveness. In: Aromataris E, Munn Z (Editors). Joanna Briggs Institute Reviewer's Manual. The Joanna Briggs Institute, 2017. https://doi.org/10.46658/JBIRM-17-03. https://scholar.archive.org/work/rovb2z4agjfgzbfgorwodicnwa/access/wayback/https://wiki.jbi.global/download/temp/pdfexport-20201106-061120-2129-14707/MANUAL-3178527-061120-2129-14708.pdf?contentType=application/pdf
- Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557-560. https://doi.org/10.1136/bmj.327.7414.557. https://www.bmj.com/content/327/7414/557.short.
- Borenstein M, Hedges LV, Higgins JP, Rothstein HR. Introduction to Meta-Analysis. John Wiley & Sons, 2021. https://www.agropustaka.id/wp-content/uploads/2020/04/agropustaka.id_buku_Introduction-to-Meta-Analysis.pdf.
- * Jalambadani Z, Garmaroodi G, Yaseri M, Tavousi M, Jafarian K. Education based on theory of planned behavior over sexual function of menopausal women in Iran. J Mid-life Health. 2017;8:124-9. https://doi.org/10.4103/jmh.JMH_44_17. https://journals.lww.com/jomh/fulltext/2017/08030/Education_Based_on_Theory_of_Planned_Behavior_over.5.aspx.
- *Kamalak H, Aksoy Derya Y. The effects of motivational interviewing on sexual quality of life and sexual self-efficacy in postmenopausal women with sexual dysfunction. [Doctoral Thesis]. Malatya, Türkiye: Department of Midwifery, Inonu University Institute of Health Sciences; 2023. https://journals.lww.com/menopausejournal/_layouts/15/oaks.journals/downloadpdf.aspx?an=00042192-990000000-00362
- *Mohammadi M, Peyman N, Hossainabadi M, Ghavami V, Tehrani H. Effect of sexual health education on sexual function and satisfaction of menopausal migrant women: an application of the theory of planned behavior. BMC Public Health. 2024;24:1626. https://doi.org/10.1186/s12889-024-19162-w.
- *Nazarpour S, Simbar M, Ramezani-Tehrani F, Alavi-Majd H. Effects of sex education and Kegel exercises on the sexual function of postmenopausal women: a randomized clinical trial. J Sex Med. 2017;14:959–967. https://doi.org/10.1016/j.jsxm.2017.05.006 https://academic.oup.com/jsm/article/14/7/959/6973443
- Egger M, Smith GD, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629-634. https://doi.org/10.1136/bmj.315.7109.629.
- Scavello I, Maseroli E, Di Stasi V, Vignozzi L. Sexual health in menopause. Medicina (Kaunas). 2019;55(9):559. https://doi.org/10.3390/medicina55090559. https://www.mdpi.com/1648-9144/55/9/559
- Stojanovska L, Apostolopoulos V, Polman R, Borkoles E. To exercise, or, not to exercise, during menopause and beyond. Maturitas. 2014;77(4):318-23. https://doi.org/10.1016/j.maturitas.2014.01.006. https://www.sciencedirect.com/science/article/pii/S0378512214000255
- Jorge MP, Santaella DF, Pontes IM, Shiramizu VK, Nascimento EB, Cabral A, Lemos TM, Silva RH, Ribeiro AM. Hatha Yoga practice decreases menopause symptoms and improves quality of life: A randomized controlled trial. Complement Ther Med. 2016;26:128-35. https://www.sciencedirect.com/science/article/pii/S0965229916300395
- Monteleone P, Mascagni G, Giannini A, Genazzani AR, Simoncini T. Symptoms of menopause global prevalence, physiology and implications. Nat Rev Endocrinol. 2018;14(4):199-215. https://doi.org/10.1038/nrendo.2017.180. https://www.nature.com/articles/nrendo.2017.180